Nanotechnology offers a range of options to lead to biology. Listed here I'll current illustrations wherever nanofabrication – a chance to make confined buildings with Proportions at will – is made use of to look at the biophysics of one molecules and cells. I'll existing some illustrations from our lab:
But how can morality, the dignity from the individual, my working experience with the indicating of daily life, stick to through the motion of atoms? A purely naturalistic viewpoint fails here; a Christian viewpoint, I feel, is a much more fair solution to interpret these areas of actuality.’
, Groningen scientists existing the outcomes of their initiatives to help make labs more sustainable and provide strategies for other labs.
2007, initial authentic-time detection of strand Trade in homologous recombination by RecA; discovery of a very low persistence duration of ends of microtubules; and resolved the system of biosensing with carbon nanotubes
2012, discovery that nucleoid occlusion underlies the precision of bacterial cell division; and to start with ever study with the dynamics DNA supercoils and the discovery of supercoil hopping
Experimental phase diagram of negatively supercoiled DNA measured by magnetic tweezers and fluorescence,
What distinguishes biology from chemistry is these factors collectively make up a dwelling technique. The trick of mentioned life, I believe, lies during the interactions, the interplay of These molecules. The big concern regarding the origin of everyday living continues to be unanswered. How did we at any time evolve from simple molecules to the extremely intricate systems we see right now? We do not know. I want to operate on these kinds of massive, open up concerns.’
Nanopores symbolize a chic and flexible Resource to evaluate solitary molecules. We investigation novel detection modes with stable-point out nanopores along with many methods to measure proteins with nanopores. Assignments encompass the subsequent:
2003, demonstrated the initial biosensors made out of a carbon nanotube; resolved the composition and system of DNA repair service proteins; and discovery of a brand new strategy for fabricating strong-condition nanopores for DNA translocation
Bulk-surface area coupling identifies the mechanistic link amongst Min-protein styles in vivo As well as in vitro
‘The idea that There is certainly this type of detail as a beginning, ceesdekker.net a huge bang, is by now a fascinating signpost to think about that there was a creator. But far more commonly, and on The premise of pure rationality, I also get there in a Christian interpretation of truth. An atheistic worldview is really a naturalistic worldview: essentially, there are actually only atoms and natural forces that we are able to measure.
Later on we spoke once more briefly due to the fact Dekker felt that our dialogue of his religion rapidly grew to become purely philosophical, While In addition it concretely assists him in his operate.
Visualization of unstained DNA nanostructures with advanced in-concentrate transmission electron microscopy tactics
The biophysicist from Delft – who is Just about the most cited scientists within the Netherlands For several years – can take his accountability to lead towards the explanation and popularisation of his work within the border of physics and biology particularly severely and routinely appears during the media; Otherwise to speak about his operate, then about the relationship between science and his Christian religion.